amino-terminal propeptide (PINP) antibody and antigen (Recombinant protein)

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Diagnostic amino-terminal propeptide (PINP) antibodies (anti-amino-terminal propeptide, anti-PINP) and antigens (recombinant amino-terminal propeptide (PINP) protein) for Metabolic diseases PINP detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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제품 정보

Catalog No.	Description	US $ Price (per mg)
GMP-h-PINP-Ag01	Recombinant human PINP Protein	$3090.00
GMP-h-PINP-Ab01	Anti-human PINP mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PINP-Ab02	Anti-human PINP mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PINP-Ab03	Anti-human PINP human monoclonal antibody (mAb)	$1953.00
GMP-h-PINP-Ab04	Anti-human PINP human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

제품 설명

Cat No. of Pruducts	GMP-h-PINP-Ag01
Product Name	Recombinant human PINP Protein
Target/Biomarker	amino-terminal propeptide (PINP)
Alias of Target/Biomarker	#N/A
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	amino-terminal propeptide (PINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation
Products description	Recombinant Human amino-terminal propeptide (PINP) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PINP-Ab01,GMP-h-PINP-Ab02
Product Name	Anti-human PINP mouse monoclonal antibody (mAb)
Target/Biomarker	amino-terminal propeptide (PINP)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human amino-terminal propeptide (PINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human PINP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PINP-Ab03,GMP-h-PINP-Ab04
Product Name	Anti-human PINP human monoclonal antibody (mAb)
Target/Biomarker	amino-terminal propeptide (PINP)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human amino-terminal propeptide (PINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human PINP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

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Target/Biomarker 정보

Procollagen type I propeptides are derived from collagen type I, which is the most common collagen type found in mineralized bone. In bone, collagen is synthesized by osteoblasts in the form of procollagen. This precursor contains a short signal sequence and terminal extension peptides: amino-terminal propeptide (PINP) and carboxy-terminal propeptide. These propeptide extensions are removed by specific proteinases before the collagen molecules form. Both propeptides can be found in the circulation and their concentration reflects the synthesis rate of collagen type I. Although collagen type I propeptides may also arise from other tissues (such as the skin, vessels, fibrocartilage, and tendons), most nonskeletal tissues exhibit a slower turnover than bone, and contribute very little to the circulating pool of PINP. PINP is considered the most sensitive marker of bone formation and it is particularly useful for monitoring bone formation therapies and antiresorptive therapies; it is recommended that the test be performed at baseline before starting osteoporosis therapy and performed again 3 to 6 months later.

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