Anti-DM1/DM4 (Maytansinoid) monoclonal antibody (mAb)

Anti-DM1/DM4 monoclonal antibody for ADC has Maytansinoid as the highly toxic payload for antibody drug conjugates. This effectively transports DM1/DM4 to cancer cells, inhibits microtubule formation, halts cell cycle and triggers apoptosis only in cancerous cells but the normal cells are less affected for targeted anti-cancer therapy.

Check the application of Maytansinoid (DM1/DM4) in ADCs


주문 정보


Catalog No. Product Name Size Price(In USD)
GTU-Bios-Maytansinoids-Ab-1 Anti-DM1/DM4 (Maytansinoid) human monoclonal antibody (mAb) 1mg 1690
GTU-Bios-Maytansinoids-Ab-2 Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb) 1mg 1690
GTU-Bios-Maytansinoids-Ab-3 Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb) 1mg 1690

Size: 1mg | 10mg | 100mg


설명


Anti-DM1/DM4 (Maytansinoid) human monoclonal antibody (mAb)

Cat No. GTU-Bios-Maytansinoids-Ab-1
Product Name Anti-DM1/DM4 (Maytansinoid) human monoclonal antibody (mAb)
Target Maytansinoid (DM1/DM4)
Expression platform mammalian cell
Isotypes Human IgG1
Bioactivity validation Maytansinoid (DM1/DM4) binding, Competitive immunoassay validation (Competitive ELISA) in Maytansinoid (DM1/DM4) level test.
Tag hFc
Products description Anti-Maytansinoid (DM1/DM4) monoclonal antibody is expressed from mammalian cell.
Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application Competitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for DM1/DM4 payload of Antibody-drug Conjugate (ADC).
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb)

Cat No. GTU-Bios-Maytansinoids-Ab-2, GTU-Bios-Maytansinoids-Ab-3
Product Name Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb)
Target Maytansinoid (DM1/DM4)
Expression platform mammalian cell
Isotypes Mouse IgG
Bioactivity validation Maytansinoid (DM1/DM4) binding, Competitive immunoassay validation (Competitive ELISA) in Maytansinoid (DM1/DM4) level test.
Tag mFc
Products description Anti-Maytansinoid (DM1/DM4)) mouse monoclonal antibody (mAb) is expressed from mammalian cell.
Species Mouse
Purity Purity: ≥95% (SDS-PAGE)
Application Competitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for DM1/DM4 payload of Antibody-drug Conjugate (ADC).
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

참고 문헌




    Validation Data


    Click to get more Data / Case study about the product.



    연관 제품


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